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Inventi Impact: Novel Excipients

Articles

  • Inventi:pne/20153/16
    The In-vitro Lipolysis of Lipid-based Drug Delivery Systems: A Newly Identified Relationship\nbetween Drug Release and Liquid Crystalline Phase
    01-Jan-1970 Research 2016 : July - September
    Lu Xiao, Tao Yi, Ying Liu, Hua Zhou

    The purpose of this study was to offer a new insight into the microstructure changes during in vitro lipolysis of five lipid-based\ndrug delivery formulations belonging to different lipid formulation types. Five lipid-based formulations of indomethacin were\ninvestigated using an in vitro lipolysis model. During lipolysis, microstructures of the intermediate phase formed by lipolytic\nproducts were observed.The results showed that the time of liquid crystal formation during in vitro digestion for these formulations\nwas Type I > Type II > Type IIIB > Type IV > Type IIIA (

    How to Cite this Article
    CC Compliant Citation: Lu Xiao, Tao Yi, Ying Liu, and Hua Zhou,\nâ??The In Vitro Lipolysis of Lipid-Based Drug Delivery Systems: A\nNewly Identified Relationship between Drug Release and Liquid\nCrystalline Phase,â? BioMed Research International, vol. 2016,\nArticle ID 2364317, 9 pages, 2016. doi:10.1155/2016/2364317,\nhttp://creativecommons.org/licenses/by/4.0/.
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